A remarkable and rare opportunity! This beautiful lakefront estate is nestled on an exceptional, oversized, east-facing lot on the coveted Everglades Island. Originally designed by renowned society architect Marion Sims Wyeth, the home features 7 bedrooms, 6 bathrooms, and 1 powder room, spectacular wide water views from nearly all main rooms, and boasts 175 +/- feet of direct Intracoastal frontage. Formal living room with fireplace opens to expansive, light-filled interior loggia that overlooks the swimming pool. Eat-in kitchen with large island and breakfast bar. Formal dining room with charming bay window. Breakfast room with beamed ceilings and pocket doors on either side for plenty of natural light. Paneled library with built-ins. Primary suite with large bath, dressing room, walk-in closet, and access to the spa. Fantastic outdoor spaces include large open terrace, covered loggia, courtyard with fountain, swimming pool, and boat dock with lift. Surrounded by meticulously maintained grounds and lush gardens filled with mature landscaping. Fantastic opportunity to move in, renovate, or build your own waterfront dream home!